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About
About

Located at the University of Massachusetts Chan Medical School in Worcester, MA, the Department of Molecular, Cell & Cancer Biology is a collaborative group dedicated to translating fundamental discoveries in biomedical research into novel therapeutic strategies for cancer and other diseases.
Faculty
Faculty

Our faculty make innovative, high-impact discoveries in biomedical research in molecular, cell and cancer biology.
Research
Research

Explore how our bold discoveries are redefining our understanding of how diseases start and can be treated.
Bioinformatics Core
Bioinformatics Core

The MCCB Bioinformatics Core is a unique in-house resource that provides cutting-edge bioinformatics and biostatistics support to researchers in the department.
Education
Education

MCCB is dedicated to fostering innovation and training the next generation of scientists. Learn more about how MCCB equips students and early-career researchers with the skills and knowledge to drive scientific discovery.
- Postdoctoral Training
  
  Postdoctoral Training
  
  Educational Enrichment Activities
  
  Professional Development & Support
  
  MCCB Postdoc Achievements
- Graduate Training
  
  Graduate Programs
  
  Educational Enrichment Activities
  
  Professional Development & Support
  
  Current MCCB Students
  
  MCCB Student Achievements
  
  Michael R. Green, MD, PhD, Award in Graduate Research
  
  MCCB Faculty Awards in Education
Community & Culture
Community & Culture

MCCB values a supportive workplace environment where everyone feels valued and has fair access to resources and opportunities. Learn more about how we foster a positive culture that supports and empowers all members of the department to succeed.
Support Us
Support Us

Learn more about how you can support MCCB’s fundraising initiatives to advance research at UMass Chan.
- Michael R. Green, MD, PhD, Award in Graduate Research
- UMass Chan Cancer Research Team
MCCB SharePoint

Additional Resources

Ruscetti is one of 13 early-career scientists recognized for groundbreaking, visionary research accelerating progress toward new cancer treatments and cures.

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The award recognizes Gregory as one of eight exceptional scientists whose innovative research is advancing the field of ovarian cancer.

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The all-day retreat brings together researchers studying diverse aspects of cancer biology and is a private event for the UMass Chan community.

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VIEW OPEN POSITIONS IN MCCB

The award recognizes outstanding graduate students at UMass Chan who have demonstrated research excellence.

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Conducting collaborative, cutting-edge research
to unravel molecular, cellular and genetic mechanisms of disease and translate our discoveries into innovative therapeutic strategies

Research

Explore how our bold discoveries are redefining our understanding of how diseases start and can be treated.

Education

Find out how MCCB equips students and early-career researchers with the skills and knowledge to drive scientific discovery.

Support

Learn more about how you can support MCCB’s fundraising initiatives to advance research at UMass Chan.

MCCB Recognitions & Achievements

Grants, Honors & Awards

Getting Results…

New Method Aims to Map the m3C Epitranscriptome in Cancer

Xin Yang, PhD, an Instructor in the Gregory Lab, has received an NIH R03 grant to develop a new method for mapping the 3-methylcytidine (m3C) RNA modification throughout the mRNA transcriptome in cancer.

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More Achievements

Recent Publications

Chao and Fazzio. R-loops shape the H2A.Z landscape and promote balanced lineage allocation during differentiation. Genome Res, 2026. Article | Fazzio Lab
Huang et al. Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease. Sci Adv, 2026. Article | Wang Lab
Tao et al. Dynamic S-acetylation of GSDMA regulates pyroptosis. ACS Chem Biol, 2026. Article | Mao Lab
Rai & Bergmann. AlphaFold3-based modeling uncovers the dynamic structural interface between full-length IAP antagonists and DIAP1 for apoptosis regulation in Drosophila. Cell Commun Signal, 2026. Article | Bergmann Lab
Lee et al. Interaction of IRS2 with PLK1 protects cells from mitotic stress. Cell Death Dis, 2026. Article | Shaw Lab

More Publications...

Highlights from UMass Chan News

Getting Results…

Junior Faculty Development Program celebrates 28 graduates

The 28 UMass Chan Medical School faculty members who completed the Junior Faculty Development Program this year graduated from the program on June 9.

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